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The Worst Foods for Gut Health (And What to Eat Instead!)

Evidence Based

iHerb has strict sourcing guidelines and draws from peer-reviewed studies, academic research institutions, medical journals, and reputable media sites. This badge indicates that a list of studies, resources, and statistics can be found in the references section at the bottom of the page.

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Key Takeaways

  • Certain foods may disrupt digestive balance: Diets high in ultra-processed foods, added sugars, and low-fiber ingredients can affect gut health over time.
  • Artificial sweeteners and alcohol may influence the microbiome: Research has explored how these substances can affect gut bacteria and digestion.
  • Low fiber intake can impact digestive function: Fiber helps support regularity and provides fuel for beneficial gut bacteria.
  • Highly processed foods can affect more than digestion: These eating patterns are often lower in fiber and may provide fewer nutrients that help support microbiome diversity.
  • Overall, eating patterns matter more than any single food: Variety, fiber intake, and long-term dietary habits all play a role in gut health.

Americans get over half of their calories from ultra-processed junk foods and collectively spend $97.8 billion every year on gut-related health problems.

Coincidence? Not according to research on the worst foods for gut health. Science shows that junk food can disrupt your microbiome and damage your gut, but it also reveals alternatives that can restore balance and help you heal.

What Are the Worst Foods for Gut Health?

Foods commonly considered “junk food” — like fast food, fried food, candy, and commercially prepared baked goods—are often refined or ultra-processed. They go through multiple production steps before landing on store shelves, many of which may be responsible for their effects on gut health.

Refined foods include sugar, white flour, and some vegetable oils, which are stripped of important nutrients during processing. Ultra-processed foods are made on an industrial scale using ingredients like colorings, flavorings, preservatives, stabilizers, or emulsifiers to create specific appearances, textures, and flavors.

How Junk Foods Affect the Gut

Although these ultra-processed foods can be convenient when life gets busy, they’re not so convenient for your gut. When you eat junk food, it:

  • Deprives beneficial gut microbes of fiber, leading to dysbiosis and a loss of microbial richness.
  • Increases the number of disease-causing bacteria called pathobionts in your gut.
  • May cause dysbiosis by promoting the growth of microbes not normally present in large numbers.
  • Can disrupt the gut microbiome in ways that affect your metabolism.
  • May promote microbiome changes associated with colon disease.

But inflammation seems to be the biggest reason why junk foods are the worst foods for gut health. A steady diet of refined and ultra-processed fare allows pro-inflammatory microbes to flourish in your gut, which can damage your gut lining and contribute to inflammation elsewhere in your body.

These changes may even affect your kids or grandkids if junk food remains a dietary staple. One study in mice showed that a lack of fiber progressively reduced the number of different microbes in the gut over several generations. Reintroducing fiber along with targeted probiotics was the only way to impact the changes.

Top Foods to Avoid for Better Gut Health

Some junk foods affect your gut more than others. Here’s how a few of the biggest offenders disrupt your health:

  • Added sugars are pro-inflammatory, which can irritate your colon and increase the likelihood of leaky gut. Eating sugar is also associated with dysbiosis.
  • Artificial sweeteners like aspartame, saccharin, and sucralose don’t break down fully during digestion. When they reach the colon, these sweeteners can increase bad gut bacteria and promote leaky gut. They can even kill the cells that line the gut when consumed in large amounts.
  • Fried food can reduce the number of different microbial species in your gut. It can also cause systemic inflammation by promoting bacterial toxins called endotoxins.
  • Red and processed meats have been shown to damage the gut lining. During digestion, red meat breaks down into compounds that can damage cells and increase the risk of colon cancer. And, like fried food, meat can introduce endotoxins that promote inflammation.

If these foods have been staples of your diet, don’t worry. You can balance your microbiome, reduce inflammation, and heal leaky gut by replacing junk foods with gut-friendly alternatives

The Worst Foods for Gut Health: Alternatives and Healing

To reverse gut damage from junk food, start by upping your intake of fiber-rich whole and minimally processed foods like vegetables, fruits, whole grains, and beans. Beans are especially high in a beneficial fiber called resistant starch, which you can also get from sweet potatoes, Jerusalem artichokes, and reheated pasta. Consuming fiber from these sources helps promote a diverse population of beneficial microbes and helps you recover from dysbiosis.

Walnuts, almonds, whole soy products, berries, and dark-colored fruits contain antioxidant polyphenols that can repair gut damage and restore balance in your microbiome. Fermented foods are also popular for gut health because they contain probiotic bacteria. Although these microbes don’t hang around in your gut for very long, they can have beneficial effects as they pass through.

Diversity in your diet is important, so take the opportunity to try as many different types of whole and minimally processed foods as you can. As you replace junk foods with these alternatives, your meat and fat intake will naturally go down, which limits your exposure to endotoxins and reduces inflammation.

Take it slow when you start your journey to better gut health. Small steps are easier to take and can help you avoid some of the discomfort that may occur if you’re not used to eating high-fiber or fermented foods.

If you don’t start to feel better in a few months after getting rid of junk food, consider getting specific, personalized recommendations from a nutrition professional who has experience with gut health and gastrointestinal disorders. With the right mix of foods to nourish your microbiome, you’ll start to feel positive changes that will motivate you to maintain your new gut-friendly habits. 

References: 

  1. Arnone, D., Vallier, M., Hergalant, S., Chabot, C., Ndiaye, N. C., Moulin, D., Aignatoaei, A. M., Alberto, J. M., Louis, H., Boulard, O., Mayeur, C., Dreumont, N., Peuker, K., Strigli, A., Zeissig, S., Hansmannel, F., Chamaillard, M., Kökten, T., & Peyrin-Biroulet, L. (2021). Long-term overconsumption of fat and sugar causes a partially reversible pre-inflammatory bowel disease state. Frontiers in Nutrition, 8, Article 758518.
  2. Flannery, J., & Healthline Editorial Team. (2023). Polyphenol-rich foods: Benefits, sources, and daily requirements. Healthline Medical Reference.
  3. Gao, J., Guo, X., Wei, W., Li, R., Hu, K., Liu, X., Jiang, W., Liu, S., Wang, W., Sun, H., Wu, H., Zhang, Y., Gu, W., Li, Y., Sun, C., & Han, T. (2021). The association of fried meat consumption with the gut microbiota and fecal metabolites and its impact on glucose homoeostasis, intestinal endotoxin levels, and systemic inflammation: A randomized controlled-feeding trial. Diabetes Care, 44(9), 1970–1979.
  4. Gibney, M. J. (2019). Ultra-processed foods: Definitions and policy issues. Current Developments in Nutrition, 3(2), Article nzy077.
  5. Greger, M. (2016, November 28). The leaky gut theory of why animal products cause inflammation (Video Article). NutritionFacts.org.
  6. Greger, M. (2018, February 16). The exogenous endotoxin theory (Video Article). NutritionFacts.org.
  7. Greger, M. (2019, June 10). Is heme iron the reason meat is carcinogenic? (Video Article). NutritionFacts.org.
  8. Greger, M. (2022, October 24). Introduction to the human microbiome and microbial ecology (Clinical Topic Hub). NutritionFacts.org.
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  10. Li, P., & Livestrong Editorial Team. (2024). The worst foods for gut health: Structural disruptors and inflammatory triggers. Livestrong Reference Series.
  11. Martinez-Medina, M., Denizot, J., Dreux, N., Robin, F., Billard, E., Bonnet, R., Darfeuille-Michaud, A., & Barnich, N. (2014). Western diet induces dysbiosis with increased E. coli in CEABAC10 mice, alters host barrier function, and favors AIEC colonization. Gut, 63(1), 116–124.
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  13. National Institute of Diabetes and Digestive and Kidney Diseases. (2023). Digestive diseases health statistics for the United States. U.S. National Institutes of Health.
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DISCLAIMER: These statements have not been approved by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent disease.